OCI Sharing:CFSA releases Kanzan flower and other 2 novel food ingredients for public comments

product name

Kanzan flower

basic information

Source: Flowers of  Cerasus serrulata ‘Sekiyama’ (Cerasus serrulata ‘Sekiyama’) of the Rosaceae Plumaceae.

Other information

 requiring explanation

1. infants, pregnant women and lactating women shall not eat, labels and instructions should be marked unsuitable for people. 
2. Food safety indicators shall be implemented in accordance with the provisions of other vegetable products.

product name

Pyrroloquinoline quinone disodium（PQQ）salt

basic information

Molecular Formula: C₁₄H₄N₂Na₂O₈

Molecular Weight: 374.17

chemical structural formula:

Brief introduction of

production process

Using 6-amino-5-methoxy-1-hydro-indole-2-carboxylic acid ethyl ester and 2-oxoglutaenedioic acid dimethyl ester as raw materials, through the coupling reaction, the formation of quinoline ring, It is made by oxidation reaction, ester hydrolysis reaction and refining process.

Recommended serving size

≤20 mg/d

quality requirement

 character 

Reddish brown powder

Pyrroloquinoline quinone disodium（PQQ）salt (Calculated on dry basis)

≥98.0%

moisture content 

≤12.0%

Other information

requiring explanation

1. Use range and maximum use amount: beverages (40 mg/kg, solid beverages are converted according to the volume of liquid after preparation). 2. Infants, pregnant women and breastfeeding women are not suitable for consumption, labels and instructions should indicate that the unsuitable people. 3. For the detection method of pyrroloquinoline quinone disodium salt content, please refer to the specific method detection. 4.Food safety indicators must meet the following requirements:

Pb, mg/kg

≤0.5

As, mg/kg

≤1.0

Cd, mg/kg

≤0.1

Hg, mg/kg

≤0.1

total plate count ,CFU/g

≤1000

Escherichia coli,MPN/g

≤3.0

Mold and yeast,CFU/g

≤100

Salmonella,/25g

Negative

Staphylococcus aureus,/25g

Negative

raw material name

background material

Precautions

Kanzan flower

Kanzan flower is a flower of Cerasus serrulata 'Sekiyama', a genus of Rosaceae, which has been widely used as vegetable or food material in Japan, Korea and Taiwan of China for many years. China began to import the planting of Guan Shan cherry in the 1990s. At present, guan Shan cherry is widely planted in China and has a history of folk consumption in Shandong,

Zhejiang,Jiangsu and other provinces. 

In view of the insufficient data on the safety of Kanzan flower in infants, pregnant women and lactating women, from the risk prevention principle, it is not suitable for these people to eat, labels and instructions should be marked unsuitable people. 

The food safety index of the raw material is in accordance with the provisions of other vegetable

products in China's current

national food safety standards. 

Pyrroloquinoline quinone disodium（PQQ）salt

6-amino-5-methoxy-1-hydro-indole-2-carboxylic acid ethyl ester and 2-oxoglutaenedioic acid dimethyl ester as raw materials, the quinoline ring is formed by coupling the ring reaction , Oxidation reaction, ester hydrolysis and refining and other processes. Pyrroloquinoline quinone disodium salt naturally exists in a variety of food such as milk, eggs, spinach and so on. The purity of the declared product is ≥98%.

Pyrroloquinoline quinone disodium salt has obtained US GRAS certification and can be used as a raw material for energy drinks, sports drinks, electrolyte drinks and bottled water and other food;which are used as dietary supplements or natural health food in EU and Canada; and is classified in food and medicine Divided into non-drug category in Japan.

The recommended consumption of this product is ≤20 mg/day (that is, the recommended consumption of pyrroloquinoline quinone disodium salt with a content of 98% is 20 mg/day, and exceeding this content is converted according to the actual content). Use range and maximum use amount: beverages (40 mg/kg, solid beverages are converted according to the volume of liquid after preparation).

In view of the lack of information on the safety of pyrroloquinoline quinone disodium salt in infants, pregnant women and lactating women, considering the principle of risk prevention, the above-mentioned people are not suitable for consumption, and the label and instructions should indicate that they are not suitable for people. The food safety index of the raw material shall be implemented in accordance with the announcement.